ChemInform Abstract: Extended Aromatic Furan Amidino Derivatives as Anti-Pneumocystis carinii Agents

1999

furan derivatives

furan derivatives R 0060 Extended Aromatic Furan Amidino Derivatives as Anti-Pneumocystis — The activity of nine new title compounds (II)–(IV) 11 - 121 carinii Agents. against Pneumocystis carinii is tested in vivo in comparison with parent compound (Ia) and its derivatives (Ib) and (Ic). Compounds (Ib), (IIb), and (IVb) are more active than (Ia), but less active than (Ic). — (HOPKINS, K. T.; WILSON, W. D.; BENDER, B. C.; MCCURDY, D. R.; HALL, J. E.; TIDWELL, R. R.; KUMAR, A.; BAJIC, M.; BOYKIN, D. W.; J. Med. Chem. 41 (1998) 20, 3872-3878; Dep. Chem., Ga. State Univ., Atlanta, GA 30303, USA; EN)

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