ChemInform Abstract: Regiospecific Synthesis of α-Amino Keto Acetals (β,β- Dialkoxyamines)

200817.fm Seite 29 Dienstag, 25. März 2008 8:48 08

2008

Ring closure reactions O 0130 Regiospecific Synthesis of Disubstituted Pyridin-2-ones and Trisubstituted Phenols with Vinamidinium Salts. — The regiochemistry of the reaction of β-keto17- 028 -amides (I) or (IV) with vinamidinium salts (II) depends on the substitution at the ω-position of (I) or (IV). Hydrogen- or alkyl-substituted compounds afford pyridin-2-ones of type (III), whereas aryl-substituted compounds give trisubstituted phenols of type (V). — (JAMELEDDINE, K.; THOURAYA, G.; ADNEN, H. A. M.; BECHIR*, B. H.; Synth. Commun. 37 (2007) 22, 3939-3944; Lab. Synth. Org. Asymetrique Catal. Homogene, Fac. Sci., 5019 Monastir, Tunisia; Eng.) — M. Bohle