ChemInform Abstract: Tetrahydrofuran α-Azido Esters: Precursors of Anomeric α-Amino Acid Monomers via Radical Bromination

1999

carbohydrates

carbohydrates U 0500 Tetrahydrofuran α-Azido Esters: Precursors of Anomeric α-Amino 42 - 228 Acid Monomers via Radical Bromination. — Highly selective radical bromination of protected carbohydrate C-glycosyl derivatives such as (I) and (IV) gives α-bromo esters which undergo displacement by azide to afford α-azido esters either as a single stereoisomer or as a diasteromeric mixture. — (SMITH, MARTIN D.; LONG, DANIEL D.; MARTIN, ANGELES; CAMPBELL, NEIL; BLERIOT, YVES; FLEET, GEORGE W. J.; Synlett (1999) 7, 1151-1153; Dyson Perrins Lab., Oxford Cent. Mol. Sci., Oxford Univ., Oxford OX1 3QY, UK; EN)

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