International Journal of Green Nanotechnology, 4:511–515, 2012 c Taylor & Francis Group, LLC Copyright ISSN: 1943-0892 print / 1943-0906 online DOI: 10.1080/19430892.2012.739454
BIOMEDICINE
Downloaded by [Mohammad Reza Dayer] at 22:13 20 March 2013
In Silico Study of Global Structure of Human Serum Albumin Farideh Zergani Razieh Roohizadeh Mohammad-Reza Dayer Mehrdad Namdari Abdolhady Farokhnia Yaghoub Sobhany Omid Ghayour
ABSTRACT. Using a molecular dynamics (MD) method, the structural changes of albumin with temperature in the presence of salts provide mechanistic insights about the structural changes and deterministic factors that participate in albumin denaturation. These studies may be helpful in understanding the mechanism by which albumin helps the body in controlling its temperature against
Received 2 May 2012; accepted 1 August 2012. The financial support of Shahid Chamran University of Ahwaz and Khouzestan Science and Research Unit, Azad Islamic University, Ahvaz, Iran, is acknowledged. Farideh Zergani is affiliated with the Department of Chemistry, Science and Research Branch, Islamic Azad University, Khouzestan, Iran. Razieh Roohizadeh is affiliated with the Department of Chemistry, Science and Research Branch, Islamic Azad University, Khouzestan, Iran. Mohammad-Reza Dayer is affiliated with the Department of Biology, Faculty of Sciences, Shahid Chamran University, Ahvaz, Iran. Mehrdad Namdari is affiliated with the Department of Mathematics, Faculty of Computer and Mathematical Sciences, Shahid Chamran University, Ahvaz, Iran. Abdolhady Farokhnia is affiliated with the Department of Mathematics, Faculty of Computer and Mathematical Sciences, Shahid Chamran University, Ahvaz, Iran. Yaghoub Sobhany is affiliated with the Department of Chemistry, Science and Research Branch, Islamic Azad University, Khouzestan, Iran. Omid Ghayour is affiliated with the Department of Mathematics, Faculty of Computer and Mathematical Sciences, Shahid Chamran University, Ahvaz, Iran. Address correspondence to Mohammad-Reza Dayer, Department of Biology, Faculty of Sciences, Shahid Chamran University, Ahvaz, Iran. E-mail:
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