P.213 Oral mucosal melanoma. Report of two cases

Posters the group of control indices (p = 0.02, 0.04). Specific antioxidant activity level of oral fluid for females of the 3rd group was greater than for males (p = 0.03). Conclusions: Achieved results confirm is advisable to apply antioxidant therapy for treatment of studied age groups of patients. P.212 Oral manifestations of neurofibromatosis 1: a case report

Oral surgery

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Results: Both patients were recovered within a week of the intervention, and with good quality of life. The first one developed cerebral and pulmonary metastases at 6 months, and continuing palliative care. The second one is disease-free 2 months after intervention. Conclusions: The prognosis for patients with oral melanoma is very poor. Ablative surgery with tumor-free margins remains the treatment of choice. Medical therapy is not often beneficial for treating oral melanoma.

A. Apaydin, T. Can. Istanbul University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Turkey The term neurofibromatosis (NF) is used to a group of genetic disorders that primarily affect the cell growth of neural tissues. There are two forms of NF: neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2). NF1 affects about 1 in 3000 newborns and 1 000 000 people worldwide. The diagnosis of NF1 is based on the identification of two or more features from a de-fined list of NF1-associated clinical criteria established by National Institutes of Health Con-sensus Development Conference. Cafe-au-lait spots, skin fold freckling in the axillary, ingui-nal, and neck regions, and Lisch nodules are common pigmentary abnormalities. The aim of this case report is to emphasize the fact that NF1 is one of the most common genetic diseases and oral manifestations can be observed very often. Because of this fact dentists should be aware of the characteristics of this disease. A 17-year-old male patient was referred to our clinic for a very painful, non-ulcerated swelling at the buccal aspect of the mandibular left premolars. Reviewing the medical history the patient had been diagnosed NF1. Radiographic examinations revealed an enlargement of left mandibular canal and mental foramen. the lesion has been excised and diagnosed as neurofibroma. In the postoperative period the patient has been reviewed regularly. The multi organ occurrence of NF1 requires a multidisciplinary approach. Since there is no cure for NF1, the management must be toward prevention and control of the complications. It is important that dentists conduct long-term follow-up because of the potential for local complications and the known risk of malignant transformation. P.213 Oral mucosal melanoma. Report of two cases A. Apaydin, T. Can, F. Garc´ıa Pire, V. Vazquez Marcos, B. Rodriguez Caballero, G. Herrera Calvo, M. Saldana Rodriguez, B. Garcia Montesinos, R. Saiz Bustillo, T. Gonzalez Teran, F. Garcia Reija, S. Sanchez Santolino, J. Garmendia Avendano, C. Temino Malo . Hospital Universitario Marques de Valdecilla, Santander, Spain Objectives: The mucosal melanoma is a rare and aggressive disease, when present in the oral cavity normally appears in upper gums or palate. Mucosal melanomas account for less than 2% of all melanomas. Of these, 55% occur in the head and neck region, the annual incidence of oral melanoma is very low. Methods: Report of two cases. We present two new cases of primary oral mucosal melanoma. The first case was a patient 77 years old with 2 maxillary and mandibular lesions. The second one is a 33-year-old patient with a lesion on the hard palate with 3 cm diameter. On physical examination, no clinically atypical or suspicious nevi were observed on the skin or scalp in both patients. The biopsy was informed as melanoma in all cases. TC had no signs of regional extension of the disease or distant metastasis. The treatment consisted of ablative surgery of tumors in both cases. Left Supraomohyoid cervical lynphadenectomy was done in the first patient. In the second case was performed sentinel node biopsy resulting negative.

P.214 Ostiomeatal complex in odontogenous maxillary sinusitis H. Wanyura, M. Uliasz, K. Abed. Department of CranioMaxillofacial Surgery, Medical University of Warsaw, Warsaw, Poland Objectives: The study aimed at solving the dilemma of whether the blockage of the ostiomeatal complex in odontogenous inflammations of maxillary sinuses is primary or secondary. Methods: On the basis of clinical and radiological examinations of 110 patients it was attempted to determine the role of the ostiomeatal complex in odontogenous inflammations of maxillary sinuses. Results: The obtained results were analysed statistically and indicated a significant relationship between the following two variables: the degree of shadowing of the maxillary sinus under surgical treatment and the patency of its ostium. The percentage of patients with patent maxillary sinal ostium is in inverse proportion to the degree of its inflammatory involvement. Conclusion: The significance of the ostiomeatal complex in pathomechanism of odontogenous inflammations of maxillary sinuses is secondary. Lack of patency of the maxillary sinal ostium is secondary to the pathological process occurring in its lumen, and results from the progression of this process irrespective of the character of the odontogenous etiological factor. It is, however, primary in rhinogenic inflammations.

P.215 Postoperative occlusal force in hyperplasia of masticatory muscle K. Yamada, R. Yosikado, A. Fukuda, Y. Ogawa, K. Ito, S. Matsuda, Hi. Yoshida, T. Iseki, S. Morita. First Dpt. of Oral and Maxillofacial surgery, Osaka Dental Uni., Osaka, Japan Objective: Hyperplasia of the masticatory muscle tendon and aponeurosis is a rare disease. As splint or physical therapy was not effective, for treatment of the disease, aponeurectomy in the masseter muscle and coronoidectomy were adopted. The purpose of this study is to evaluate the change in the occlusal force of patients who underwent aponeurectomy of the masseter muscle and coronoidectomy for hyperplasia of the masticatory muscle tendon and aponeurosis. Materials and Methods: Subjects were 3 female patients, who revealed a square mandible configuration, with nonreducing disc displacement, and overlength of coronoid process has not seen. They were limited opening of the mouth ranging from 11 mm to 28 mm. Minor restriction of mouth opening were first noticed at over 10 years. 3 patients underwent bilateral aponeurectomy of the masseter muscle and coronoidectomy. For a period of 1 year after surgery, occlusal force was examined using pressure sensitive sheets, Dental Prescale (Fuji Photo Film, Co.), and the movements of the mandible were analyzed. Result: The occlusal force in 3 patients showed a tendency of recovery from 1 to 3 months, and maximal range of mouth opening was over 40 mm at 6 months after surgery. Conclusion: It is suggested that aponeurectomy of the masseter muscle and coronoidectomy is useful for the treatment of hyperplasia of the masticatory muscle tendon and aponeurosis.