Primary gastric lymphoma: a review of 45 cases

Primary

Gastric

,I. R;\VAIOLI,*lj *Medical

Oncology

hl. :\M:ZDORI,*

Department

t.Uedical

Lymphoma:

Oncolo~v

31. FAEDI,* Department,

, $Surgev Department

A Review

G. ROSTIt, S. FOLLI,: C. BARBIERI,+, G. GIORGINI,$ M. MARANGOL0.t E. EMILIANI,I( and D. .ZMADOI11*

$Patholou

” Ospedak

of 45 Cases

S. .Elaria

Department

delle

Croci”.

“Ospedale Rarlenna

G.B.

and

Morgagni-L.

/1Institute

” Ospedale

Abstract-PrimaT o/‘patients

gastric

affected

ulith

Jvmphoma

accountsfor

non-Hodgkin’s

gastric

about

2%

ofgastric

Iq’mphoma

appears

anaLv:ed

45

S.

“L.

Ortola”,

ITorli: Galwni”

Bologna,

Italy

Theprognosis

neoplasms.

better

Pierantoni”.

of Radiotherapy

than,/&

other ivmphatic

.\ites. In

a

retrosprctiue

pathologic

stud)‘,

characteristics

The main factors

71.2%1P disease ,grade

<

/hi\

between

roho undenrrent

,urgeyr

irzjkencing &mph

and patient

signiJcant

ol’erall

difference

IT not

5-yr

suroival

<

histologic

characteristics,

0.001).

The

be considered

important

and clinical

in extra-nodal

more

than

nodal

site

most

intestinal

and

disease-free

those who

had

suwiual

of patient.\

chemotherapy

of the group who had combined

crcntial

location

The higher

treatment.,.

pcndcnt

of the stage

of patients tram

with

diagnosis

Numerous nificancc

age.

disease-frcr from

neoplasm,

scrosal

of nodal

involvcmcnt

rhc disease,

seem

a significant

with

nancy gastric

after though

regional

sites,

of high

of this

number

from

sig-

studies. degrees that

patients

study

was

to verify

factors

and

thr

role of

in determining

scrics

of NHI.

records

and

treated

for primary

1973 to 1984 at thr city

hospitals

Forty-eight

of the of

OS

patients.

histo-pathologic

data

gastric

Oncology

of Forli

consccutivc

spcctivcly

considered:

Oncology

Dept.

Oncology

have

NHI,

Dcpartmcnts

and

were of malig-

casts 34

and

Ravcnna

\vcr(

of PGL wcrc rctro-

casts

14

from

from

the

thr

I:orli

Kavcnna

Dept.

X11 the histological

the unfavorable for

of firlds,

examined.

[l-4]. grades

arc

[8, 121.

prognostic

hospital

of thr

the stage

factors

of all

(DFS)

case

also

aim

The

[6-81.

location

dctcrminc

to br confirmed [Y-l I].

and

prog-

importancr

MATERIALS AND METHODS

indc-

prognostic

and various

is concrrncd,

(size

greater

treated

a pcrcentagc

on survival

therapeutic-linked

assume

chemotherapy

major

slightly

survival

different

which

the

the

that

therapy and

The

pref-

surgery,

and DFS in a homogeneous

appears

to bc the main

significance

with

40 to 60%

prnetration

influcnrc

seems NHLs

is the gastro-

in the various with

As far as histology prognostic

dose).

with

5-yr

along

radiation

extra-

for other

ranging

arc reported

Patient

wen

factors

do. The

of patients

of disease,

factors

nostic

[l-5].

(OS)

indicated

to origcases)

of the cases)

of the stomach

that

radiotherapy

of the

involved

(9%

survival

NHL

than

(cu. 20%

in the stomach

overall

fi)r primary

tend

lymphomas

tract

but

I ,_ and

in s&es

and/or

Bcsidcs

(&HL)

frequently

(GI)

or lore)

fartors,

sign$cant.

sites

Hodgkin’s

stage oj

of cases.

zvith

lymphomas

inate

histo-

the high

prognostic

INTRODUCTION NON-HODGKIN’S

the

(3 I. 17% 1’~.

penetratron

vs. 68%))

(85.6%)

ttatistical~v

are: serosal

(53.Oi%

.rurr*iz~al

shou1.r a hi