Synovial sarcoma in a premature newborn

Synovial sarcoma in a premature newborn.
Pediatr Int. 2014 Jun;56(3):e17-20. doi: 10.1111/ped.12338.
Köse D1, Annagür A, Erol C, Uğraş S, Köksal Y.

Abstract

Synovial sarcoma is rarely detected in infants, with an annual incidence of
0.5 per million. Synovial sarcoma occurs more frequently in adolescents and
young adults, with the majority of patients presenting between 15 and 40
years of age. It is extremely rare, however, in pediatric patients under 2
years of age. In the present study we examined a 3-day-old male infant born
at 32 weeks who had a mass on his left arm. Synovial sarcoma was identified
on histopathological and immunohistochemical analysis of biopsy material
acquired from the mass. On whole body magnetic resonance imaging, diffuse
metastases were detected in the bilateral lungs in the retroperitoneal
zone, in bilateral suprarenal glands, the right liver lobe, the right
kidney, and the brain. To our knowledge this is the youngest patient to be
diagnosed with synovial sarcoma in the literature.