Organic Chemistry

Novel cell-penetrating α-keto-amide calpain inhibitors as potential treatment for muscular dystrophy

Organic Chemistry / Mice / Muscular Dystrophy / Animals / Animal Model / Duchenne Muscular Dystrophy / Calpain / Amides / Molecular Structure / Cysteine Proteinase Inhibitors / Duchenne Muscular Dystrophy / Calpain / Amides / Molecular Structure / Cysteine Proteinase Inhibitors

Phenylhomophthalimide-type NOS inhibitors derived from thalidomide

Organic Chemistry / Enzyme Inhibitors / Magnetic Resonance Spectroscopy / Nitric Oxide Synthase / Thalidomide

Synthetic UDP-Furanoses as Potent Inhibitors of Mycobacterial Galactan Biogenesis

Organic Chemistry / Enzyme Inhibitors / Chemistry Biology / Recombinant Proteins / Biochemistry and cell biology / Klebsiella pneumoniae

Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi

Organic Chemistry / Treatment / Drug development / Macromolecular X-Ray Crystallography / In Vitro / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure / Animals / Naphthoquinones / Chagas disease / European / Hydrogen Bonding / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Cations / Chemical Synthesis / Molecular Structure

Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals

Organic Chemistry / Gene expression / Signal Transduction / DNA / Cell line / Humans / Gene transfer techniques / Peptides / Skin / Phosphorylation / Gene Delivery / Isoenzymes / Substrate / Amino Acid Sequence / Normal / Polyelectrolyte / Intracellular / Humans / Gene transfer techniques / Peptides / Skin / Phosphorylation / Gene Delivery / Isoenzymes / Substrate / Amino Acid Sequence / Normal / Polyelectrolyte / Intracellular

Easy access to α-amino β-oxo esters from β-enamino esters

Organic Chemistry / Amination / Amino Acid Profile

Synthesis and structural studies of rhodium(I)-catalytic precursors containing two furanoside diphosphines

Inorganic Chemistry / Organic Chemistry / Organometallic Chemistry / NMR Spectroscopy / Molecular Mechanics / Room Temperature

Synthesis and Biological Activity of Aromatic Amino Acid Phosphoramidates of 5-Fluoro-2‘-deoxyuridine and 1-β-Arabinofuranosylcytosine:  Evidence of Phosphoramidase Activity

Organic Chemistry / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Cell Division / Cell line / Humans / Mice / Animals / Aromatic amino acid / Organophosphorus Compounds / Biological activity / Humans / Mice / Animals / Aromatic amino acid / Organophosphorus Compounds / Biological activity

Perinatal Asphyxia: A Review from a Metabolomics Perspective

Organic Chemistry / Biomarkers / Metabolomics / Pregnancy / Humans / Female / Animals / Newborn Infant / Molecules / Metabolome / Female / Animals / Newborn Infant / Molecules / Metabolome

Development of CXCR3 antagonists. Part 4: Discovery of 2-amino-(4-tropinyl)quinolines

Organic Chemistry / Mice / Animals / Bioorganic and medicinal Chemistry / Quinolines / Biological Availability / Physicochemical Properties / Area Under Curve / Biological Availability / Physicochemical Properties / Area Under Curve
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