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Signal Transduction
Signal Transduction
Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades
Physiology / Mitochondria / Apoptosis / Signal Transduction / Molecular chaperones / Caspases / Mice / Animals / Methamphetamine / Male / Cell Death / Cytochrome C / Endoplasmic Reticulum / ER stress / Medical Physiology / Neurons / Transcription Factor / Calpain / Illicit Drugs / Heat Shock Proteins / Gamma-Aminobutyric Acid / Biochemistry and cell biology / DNA fragmentation / Neuronal apoptosis / Caspases / Mice / Animals / Methamphetamine / Male / Cell Death / Cytochrome C / Endoplasmic Reticulum / ER stress / Medical Physiology / Neurons / Transcription Factor / Calpain / Illicit Drugs / Heat Shock Proteins / Gamma-Aminobutyric Acid / Biochemistry and cell biology / DNA fragmentation / Neuronal apoptosis
Hedgehog–Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer
Stem Cells / Drug development / Stem Cell / Transcription Factors / Signal Transduction / Brain Tumor / Brain / Humans / Cerebral Cortex / Model System / Embryos / Brain Neoplasms / Brain Tumor / Brain / Humans / Cerebral Cortex / Model System / Embryos / Brain Neoplasms
Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation
Immunology / Immune response / Cell Biology / Mitochondria / Apoptosis / Signal Transduction / Caspases / Cell line / Allergy / Mitochondrial DNA / Humans / Reactive Oxygen Species / Mice / Animals / Cell Death / Cytochrome C / NADPH oxidase / Immunology & Cell Biology / Oxidative phosphorylation / Mitochondrial Membrane Potential / Conformational Change / Biochemistry and cell biology / Cytotoxic T cells / Immunoblotting / Signal Transduction / Caspases / Cell line / Allergy / Mitochondrial DNA / Humans / Reactive Oxygen Species / Mice / Animals / Cell Death / Cytochrome C / NADPH oxidase / Immunology & Cell Biology / Oxidative phosphorylation / Mitochondrial Membrane Potential / Conformational Change / Biochemistry and cell biology / Cytotoxic T cells / Immunoblotting
Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels
Kinetics / Mitochondria / Multidisciplinary / Signal Transduction / Cercopithecus aethiops / Mice / Animals / Heart / Myocardium / Adenylate Kinase / Isoenzymes / Potassium Channels / Transfection / Recombinant Proteins / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate / Cell Membrane / Mice / Animals / Heart / Myocardium / Adenylate Kinase / Isoenzymes / Potassium Channels / Transfection / Recombinant Proteins / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate / Cell Membrane
ADAM12 is expressed by astrocytes during experimental demyelination
Cognitive Science / Multiple sclerosis / Brain development / Signal Transduction / Lipopolysaccharide / Glutamate / Brain / Cerebral Cortex / Mice / Animals / Male / Astrocyte / Central Nervous System / Astrocytes / Hydrogen Peroxide / Lipopolysaccharides / Tumor necrosis factor-alpha / Glial Fibrillary Acidic Protein / Multi Domain / Cell Proliferation / Experimental Autoimmune Encephalomyelitis / Tumor Necrosis Factor–α (TNF) / Neurosciences / Cuprizone / Glutamate / Brain / Cerebral Cortex / Mice / Animals / Male / Astrocyte / Central Nervous System / Astrocytes / Hydrogen Peroxide / Lipopolysaccharides / Tumor necrosis factor-alpha / Glial Fibrillary Acidic Protein / Multi Domain / Cell Proliferation / Experimental Autoimmune Encephalomyelitis / Tumor Necrosis Factor–α (TNF) / Neurosciences / Cuprizone
DNA-Damage Response in Tissue-Specific and Cancer Stem Cells
Cancer / Aging / DNA damage / DNA repair / Stem Cell / Signal Transduction / Biological Sciences / DNA / Humans / Animals / Cancer Stem Cell / Neoplasms / Signal Transduction / Biological Sciences / DNA / Humans / Animals / Cancer Stem Cell / Neoplasms
ADAM8 as a drug target in pancreatic cancer
Membrane Proteins / Multidisciplinary / Western blotting / Signal Transduction / Humans / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase
ROOT ULTRAVIOLET B-SENSITIVE1/WEAK AUXIN RESPONSE3 Is Essential for Polar Auxin Transport in Arabidopsis
Signal Transduction / Biological Sciences / Plant Physiology / Mutation / Plant Roots / Arabidopsis / Membrane transport proteins / Endosomes / Meristem / Cell Membrane / Arabidopsis / Membrane transport proteins / Endosomes / Meristem / Cell Membrane
Inhibition of cerebral ischemia/reperfusion-induced injury by adenovirus expressed C-terminal amino acids of GluR6
Cognitive Science / Gene Therapy / Membrane Proteins / Western blotting / Neuronal cell death / Signal Transduction / Brain / Animals / Gene transfer techniques / Male / Cell Death / Cell Fractionation / Phosphorylation / Brain Ischemia / Cytoprotection / Neurons / Brain injury / Mitogen Activated Protein Kinase / NMDA / AMPA / Rats / Neuronal Death / Analysis of Variance / Cerebral Ischemia / Amino Acid Profile / MAPK / Reperfusion injury / Subcellular Fractions / Cell Survival / Neurosciences / Postsynaptic Density / Ad / Signal Transduction / Brain / Animals / Gene transfer techniques / Male / Cell Death / Cell Fractionation / Phosphorylation / Brain Ischemia / Cytoprotection / Neurons / Brain injury / Mitogen Activated Protein Kinase / NMDA / AMPA / Rats / Neuronal Death / Analysis of Variance / Cerebral Ischemia / Amino Acid Profile / MAPK / Reperfusion injury / Subcellular Fractions / Cell Survival / Neurosciences / Postsynaptic Density / Ad
Nuclear β-catenin promotes non-neural ectoderm and posterior cell fates in amphioxus embryos
Electron Microscopy / Lithium / Signal Transduction / Biological Sciences / Animals / Developmental / Introns / Molecular cloning / Cell Fate / Embryos / Wnt / Molecular Sequence Data / Developmental / Introns / Molecular cloning / Cell Fate / Embryos / Wnt / Molecular Sequence Data
Phosphoinositide 3-kinases: A conserved family of signal transducers
Caenorhabditis elegans / Drosophila melanogaster / Signal Transduction / Biological Sciences / Animals / Membrane Lipids / Dictyostelium / CHEMICAL SCIENCES / Substrate Specificity / Molecular Sequence Data / Membrane Lipids / Dictyostelium / CHEMICAL SCIENCES / Substrate Specificity / Molecular Sequence Data
The Arabidopsis SUMO E3 ligase SIZ1 controls phosphate deficiency responses
Multidisciplinary / Signal Transduction / Mutation / Polymerase Chain Reaction / Plant Roots / Arabidopsis / Anthocyanins / Phosphates / Adaptive Response / Lateral Root / Immunoblotting / Arabidopsis / Anthocyanins / Phosphates / Adaptive Response / Lateral Root / Immunoblotting
Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular aging
Principal Component Analysis / Aging / Kidney diseases / Signal Transduction / Biological Sciences / Mice / Female / Animals / Male / Cluster Analysis / Progeria / Age Factors / DNA binding proteins / Gene Expression Regulation / Gene expression profiling / Mice / Female / Animals / Male / Cluster Analysis / Progeria / Age Factors / DNA binding proteins / Gene Expression Regulation / Gene expression profiling
Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy
Calcium / Protein synthesis / Signal Transduction / Cats / Molecular / Cardiac Hypertrophy / Mice / Congestive Heart Failure / Animals / Phenotype / Nuclear envelope / Rats / Surface Area / Body Weight / Calcineurin / Arrhythmia / Ejection Fraction / Transgenic Mouse Technology / Heart Ventricles / Cell Volume / Histone deacetylases / Cardiac Hypertrophy / Mice / Congestive Heart Failure / Animals / Phenotype / Nuclear envelope / Rats / Surface Area / Body Weight / Calcineurin / Arrhythmia / Ejection Fraction / Transgenic Mouse Technology / Heart Ventricles / Cell Volume / Histone deacetylases
Growth Factors as Active Participants in Carcinogenesis: A Perspective
Veterinary Pathology / Signal Transduction / Humans / Epidermal Growth Factor/ErbB receptors / Animals / Fisheries Sciences / Epidermal Growth Factor / Neoplasms / Transforming Growth Factor Beta / Veterinary Sciences / Antineoplastic Agents / Fisheries Sciences / Epidermal Growth Factor / Neoplasms / Transforming Growth Factor Beta / Veterinary Sciences / Antineoplastic Agents
Glia-Derived d-Serine Controls NMDA Receptor Activity and Synaptic Memory
Long Term Potentiation / Lactation / Synaptic Plasticity / Patch-clamp and imaging techniques / Signal Transduction / Biological Sciences / Glutamate / Female / Animals / Cell / Astrocyte / Supraoptic Nucleus / Synaptic Transmission / Neurons / Astrocytes / Rats / SYNAPSES / Wistar Rats / Nervous System / Biological Sciences / Glutamate / Female / Animals / Cell / Astrocyte / Supraoptic Nucleus / Synaptic Transmission / Neurons / Astrocytes / Rats / SYNAPSES / Wistar Rats / Nervous System
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