Signal Transduction

Biomolecule-assisted Natural Computing Approaches for Simple Polynomial Algebra Over Fields

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Why do cells release vesicles?

Genetics / Cancer / Dendritic Cells / Signal Transduction / DNA / Virulence / Humans / Bacteria / Exosomes / Clinical Sciences / Neoplasms / Thrombosis / Disease Progression / Microspheres / Exosome / Antigen presenting cells / Virulence / Humans / Bacteria / Exosomes / Clinical Sciences / Neoplasms / Thrombosis / Disease Progression / Microspheres / Exosome / Antigen presenting cells

Ontogeny of Local Sarcoplasmic Reticulum Ca2+ Signals in Cerebral Arteries : Ca2+ Sparks as Elementary Physiological Events

Electrophysiology / Fluorescence Microscopy / Calcium / Cell Division / Signal Transduction / Caffeine / Female / Animals / Calcium channels / Male / Vasoconstriction / Clinical Sciences / Rats / Rat / Circulation / Potassium Channels / Sarcoplasmic reticulum / Caffeine / Female / Animals / Calcium channels / Male / Vasoconstriction / Clinical Sciences / Rats / Rat / Circulation / Potassium Channels / Sarcoplasmic reticulum

DNA Damage Response

DNA damage / DNA repair / Signal Transduction / Humans / Animals / Phosphorylation / Chromatin / Histones / Genomic instability / Phosphorylation / Chromatin / Histones / Genomic instability

Insulin-Mediated Cellular Insulin Resistance Decreases Osmotic Shock-Induced Glucose Transport in 3T3-L1 Adipocytes

Endocrinology / Signal Transduction / Biological Sciences / Insulin Resistance / Glucose / Insulin / Mice / Animals / Osmotic pressure / Phosphorylation / T cells / Phosphotyrosine / Clinical Sciences / Glucose Transport / Adipocytes / Glucose Uptake / Plasma Membrane / Tyrosine Phosphorylation / Cell Membrane / Insulin / Mice / Animals / Osmotic pressure / Phosphorylation / T cells / Phosphotyrosine / Clinical Sciences / Glucose Transport / Adipocytes / Glucose Uptake / Plasma Membrane / Tyrosine Phosphorylation / Cell Membrane

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis

Cytokines / Signal Transduction / Humans / Liver / Mice / Animals / Male / Hepatocellular Carcinoma / Hepatitis / Hyperplasia / Lipopolysaccharides / Liver regeneration / Time Factors / Necrosis / Cancer Cell / Neurosciences / Diethylnitrosamine / Gene Expression Regulation / Interleukin / Animals / Male / Hepatocellular Carcinoma / Hepatitis / Hyperplasia / Lipopolysaccharides / Liver regeneration / Time Factors / Necrosis / Cancer Cell / Neurosciences / Diethylnitrosamine / Gene Expression Regulation / Interleukin

ADAM8 as a drug target in pancreatic cancer

Membrane Proteins / Multidisciplinary / Nature / Western blotting / Signal Transduction / Humans / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Communications / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase / Humans / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Communications / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase

Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling

Immunology / Immunology of the Gut / Innate immunity / Signal Transduction / Mice / Adaptive Immunity / Animals / Biological evolution / Intestines / Microbiota / Myeloid Cells / Bone Marrow Cells / Gene Expression Regulation / Adaptive Immunity / Animals / Biological evolution / Intestines / Microbiota / Myeloid Cells / Bone Marrow Cells / Gene Expression Regulation

Human neutrophil peptides: a novel potential mediator of inflammatory cardiovascular diseases

Physiology / Atherosclerosis / Inflammation / Cardiovascular disease / Signal Transduction / Humans / American / Medical Physiology / Neutrophils / Cardiovascular Diseases / Biological markers / Humans / American / Medical Physiology / Neutrophils / Cardiovascular Diseases / Biological markers

Titanium dioxide nanoparticles cause apoptosis in BEAS-2B cells through the caspase 8/t-Bid-independent mitochondrial pathway

Titanium / Mitochondria / Apoptosis / Metal Nanoparticles / Signal Transduction / Cell line / Humans / Reactive Oxygen Species / Cytochrome C / Titanium dioxide / Cell Viability / Caspase / Cell Survival / ENVIRONMENTAL SCIENCE AND MANAGEMENT / Cell line / Humans / Reactive Oxygen Species / Cytochrome C / Titanium dioxide / Cell Viability / Caspase / Cell Survival / ENVIRONMENTAL SCIENCE AND MANAGEMENT

Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins

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CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress

Membrane Proteins / Mitochondria / Endoplasmic Reticulum Stress / Apoptosis / Signal Transduction / Cell line / Mice / Animals / Endoplasmic Reticulum / Caspase / Cell line / Mice / Animals / Endoplasmic Reticulum / Caspase

Human mesenchymal stem cells protect neutrophils from serum-deprived cell death

Cell Biology / Apoptosis / Signal Transduction / Mesenchymal stem cells / Humans / Cell Death / Neutrophils / Mesenchymal Stromal Cells / Biochemistry and cell biology / Cell Death / Neutrophils / Mesenchymal Stromal Cells / Biochemistry and cell biology

Human malaria parasites display a receptor for activated C kinase ortholog

Fluorescence Microscopy / Cell Cycle / Cell Signaling / Confocal Microscopy / Danio rerio / Western blotting / Signal Transduction / Humans / Animals / Biochemical / Life Cycle / Molecular cloning / Plasmodium falciparum / Amino Acid Profile / Molecular weight / Amino Acid Sequence / Base Sequence / Erythrocytes / Protein Binding / Chlamydomonas Reinhardtii / Full Length Movies / Oligonucleotides / Biochemistry and cell biology / Molecular Sequence Data / Western blotting / Signal Transduction / Humans / Animals / Biochemical / Life Cycle / Molecular cloning / Plasmodium falciparum / Amino Acid Profile / Molecular weight / Amino Acid Sequence / Base Sequence / Erythrocytes / Protein Binding / Chlamydomonas Reinhardtii / Full Length Movies / Oligonucleotides / Biochemistry and cell biology / Molecular Sequence Data

Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos

Psychology / Mitochondria / Signal Transduction / NO / HSP / Par / Humans / PD / Animals / Cell Death / Clinical Sciences / NMDA / Cell nucleus / Calpain / Experimental Neurology / NAD / Neurosciences / NLS / Par / Humans / PD / Animals / Cell Death / Clinical Sciences / NMDA / Cell nucleus / Calpain / Experimental Neurology / NAD / Neurosciences / NLS

The domino effect

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