Enzyme Inhibitors

5′-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells

Neuroscience / Psychology / Enzyme Inhibitors / Apoptosis / Caspases / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Enzyme / Norepinephrine / Caspase / Neuroblastoma / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester / Cell line / Cell Differentiation / Brain / Humans / Acetylcholine / Neurons / Enzyme / Norepinephrine / Caspase / Neuroblastoma / Retinoic Acid / Tretinoin / Protein Kinase / Bovine Serum Albumin / Neurosciences / Phorbol ester

2′-Epi-2′-O-acetylthevetin B induces apoptosis partly via Ca2+-mediated mitochondrial pathway in human hepatocellular carcinoma HepG2 cells

Calcium / Enzyme Inhibitors / Cell Biology / Mitochondria / Apoptosis / Signal Transduction / Mice / Animals / Hepatocellular Carcinoma / Cell Death / T cells / Apocynaceae / Human Fibroblasts / Chelating Agents / Mitochondrial Membrane Potential / Biochemistry and cell biology / Signal Transduction / Mice / Animals / Hepatocellular Carcinoma / Cell Death / T cells / Apocynaceae / Human Fibroblasts / Chelating Agents / Mitochondrial Membrane Potential / Biochemistry and cell biology

Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Hystone Deacetylase Inhibitors

Inorganic Chemistry / Organic Chemistry / Enzyme Inhibitors / Peptides / The / Oxygen / Amination / Molecular Structure / Histone deacetylase inhibitors / Oxygen / Amination / Molecular Structure / Histone deacetylase inhibitors

A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia

Microbiology / Medical Microbiology / Enzyme Inhibitors / Oxidative Stress / Humans / Mice / Animals / Drug Resistance / Oxidoreductases / Giardiasis / DRUG REPOSITIONING / Dysentery / Metronidazole / Mice / Animals / Drug Resistance / Oxidoreductases / Giardiasis / DRUG REPOSITIONING / Dysentery / Metronidazole

Semicarbazide-Sensitive Amine Oxidases: Enzymes with Quite a Lot to Do

Enzyme Inhibitors / Neurotoxicology / Humans / Animals / Enzyme / Potential Function / Xenobiotics / Substrate Specificity / Neurosciences / Potential Function / Xenobiotics / Substrate Specificity / Neurosciences

Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells

Enzyme Inhibitors / Confocal Microscopy / Apoptosis / Signal Transduction / Humans / Female / Clinical Sciences / Caspase / Histones / Ovarian Carcinoma / Human Fibroblasts / Enzymatic Activity / Biochemistry and cell biology / Nuclear Localization / DNA fragmentation / Female / Clinical Sciences / Caspase / Histones / Ovarian Carcinoma / Human Fibroblasts / Enzymatic Activity / Biochemistry and cell biology / Nuclear Localization / DNA fragmentation

Notch Promotes Radioresistance of Glioma Stem Cells

Technology / Stem Cells / Enzyme Inhibitors / Stem Cell / Signal Transduction / Biological Sciences / RNA interference / Humans / Mice / Glioblastoma / Animals / Cell Death / STEM / Peptides / Glycoproteins / Time Factors / Transfection / Cell Proliferation / Cell Survival / Radiation Tolerance / Biological Sciences / RNA interference / Humans / Mice / Glioblastoma / Animals / Cell Death / STEM / Peptides / Glycoproteins / Time Factors / Transfection / Cell Proliferation / Cell Survival / Radiation Tolerance

Vitamin E is a MIF Inhibitor

Enzyme Inhibitors / Humans / Vitamin E / Biochemical / Protein Conformation / Biochemistry and cell biology

Oral allopurinol to prevent hyperamylasemia and acute pancreatitis after endoscopic retrograde cholangiopancreatography

Enzyme Inhibitors / Pancreatitis / Humans / World / Female / Male / Acute Pancreatitis / Clinical Sciences / Aged / Middle Aged / Adult / Allopurinol / Endoscopic Retrograde Cholangiopancreatography / Male / Acute Pancreatitis / Clinical Sciences / Aged / Middle Aged / Adult / Allopurinol / Endoscopic Retrograde Cholangiopancreatography

Docosahexaenoic Acid Enhances Hepatic Serum Amyloid A Expression via Protein Kinase A-dependent Mechanism

Enzyme Inhibitors / Biological Chemistry / Biological Sciences / Lipids / Adipose tissue / Humans / Female / Hepatocellular Carcinoma / CHEMICAL SCIENCES / Middle Aged / Adult / Adipocytes / Base Sequence / Docosahexaenoic Acid / Humans / Female / Hepatocellular Carcinoma / CHEMICAL SCIENCES / Middle Aged / Adult / Adipocytes / Base Sequence / Docosahexaenoic Acid

Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene

Flow Cytometry / Immunohistochemistry / Enzyme Inhibitors / DNA damage / Apoptosis / Prevention / Western blotting / DNA / Toxicity / Mice / Applied / Animals / Male / Cell Death / Cytoprotection / Lung / tESTIS / Aryl Hydrocarbon Receptor / Apoptose / Public health systems and services research / Stilbenes / Reproductive / Spermatozoa / Somatic Cell Count / Applied Toxicology / Prevention / Western blotting / DNA / Toxicity / Mice / Applied / Animals / Male / Cell Death / Cytoprotection / Lung / tESTIS / Aryl Hydrocarbon Receptor / Apoptose / Public health systems and services research / Stilbenes / Reproductive / Spermatozoa / Somatic Cell Count / Applied Toxicology

PACAP-38 Protects Cerebellar Granule Cells from Apoptosis

Enzyme Inhibitors / Flavonoids / Apoptosis / Multidisciplinary / Neuropeptides / Cerebellum / Protein Kinases / Animals / Potassium / Neurons / Rats / Necrosis / Neuroprotective Agents / DNA fragmentation / Cerebellum / Protein Kinases / Animals / Potassium / Neurons / Rats / Necrosis / Neuroprotective Agents / DNA fragmentation

A novel amino-benzosuberone derivative is a picomolar inhibitor of mammalian aminopeptidase N/CD13

Organic Chemistry / Kinetics / Enzyme Inhibitors / Kidney / Animals / Aeromonas / Swine / Bioorganic and medicinal Chemistry / Structure activity Relationship / Low molecular weight / Molecular Structure / Aeromonas / Swine / Bioorganic and medicinal Chemistry / Structure activity Relationship / Low molecular weight / Molecular Structure

Polyphenol Oxidase Inhibitor from Blue Mussel ( Mytilus edulis ) Extract

Chemical Engineering / Food Science / Enzyme Inhibitors / Animals / Fruit / Vegetables / High Pressure Liquid Chromatography / Malus / Mytilus edulis / Food Sciences / Solanum Tuberosum / Vegetables / High Pressure Liquid Chromatography / Malus / Mytilus edulis / Food Sciences / Solanum Tuberosum

A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry

Organic Chemistry / Medicinal Chemistry / Enzyme Inhibitors / Autophagy / Humans / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes / Animals / Medicinal / Structure activity Relationship / Protein Binding / Antineoplastic Agents / Alkynes

Myeloma-reactive allospecific cytotoxic T lymphocytes lyse target cells via the granule exocytosis pathway

Flow Cytometry / Enzyme Inhibitors / Humans / Multiple Myeloma / Monoclonal Antibodies / Anti-Bacterial Agents / CTL / Tumor necrosis factor-alpha / Adoptive Transfer / Macrolides / Anti-Bacterial Agents / CTL / Tumor necrosis factor-alpha / Adoptive Transfer / Macrolides

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